Antibodies, Auto

◆ Anticentomere antibody
◆ Anti-DNA antibody
◆ Antiglomerular basement membrane antibody
◆ Antimicrosomal antibody
◆ Antimitochondrial antibody
◆ Antimyocardial antibody
◆ Antineutrophil cytoplasmic antibody (ANCA)
◆ Antinuclear antibody (ANA)
◆ Antiparietal cell antibody
◆ Antiscleroderma antibody (SCL 70)
◆ Antismooth muscle antibody
◆ Sjögren syndrome antibody (SS-A)

 Negative. Reference ranges and measurement units for
individual tests vary as does the amount of detectable antibody
that constitutes a positive result. Results may be reported as the
amount of antibody detected and if the values are considered
negative, positive, or equivocal.

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■ Autoantibodies are proteins created by the immune system
that attack the body’s own tissues or organs.
■ Autoantibodies represent a failure by the immune system
to distinguish between foreign proteins and the body’s own
tissues.
■ Elevated autoantibody levels are found in people with
autoimmune disorders such systemic lupus erythematosus
(SLE).
■ Autoimmune disorders may be organ specific as in Graves’
disease, or systemic, as in vasculitis.