Male: 107–139 mL/min; SI units: 1.78–2.32 mL/s. Female: 85–105
mL/min; SI units: 1.45–1.78 mL/s.
. Timed urine sample (12 or 24 hr) with a blood sample taken
the morning of or sometime during the test.
■ Creatinine clearance refers to the amount of blood that can
be cleared of creatinine in 1 min.
■ It is calculated using the volume of urine, the amount of
creatinine excreted, and the amount of creatinine in the
blood.
■ It is used to determine safe dosing of nephrotoxic drugs.
Creatinine clearance of 10–20 mL/min is indicative of renal
failure and the need for dialysis.
